The LS TB would be compatible. The TPS for sure, and I believe the IAC was a carry over from the older design, so it should be compatible as well.
No, 2 - 2" holes do not = 1 - 4" hole.
You have to look at area. I can't seem to work out the equation right now, but a 4" hole would have almost twice the area of 2-2" holes.
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