It can be done if you find a way to hold the MCU in reset while you flash the ROM.
I haven't paid attention to MCU architecture, but it "should" have a RST pin. Before Moates came out with the Ostriches I had an old school EconoROM 3, it would pulse the RST pin of whichever MCU after flashing to reboot it.
There is no mechanical problem so difficult that it can not be overcome by brute strength and ignorance.
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